Archives for April 2010

04/13/2010

Cui Z, Hou J, Chen X, Li J, Xie Z, Xue P, Cai T, Wu P, Shi L, Xu T, Yang F.
J Proteome Res. 2010 Apr 10. [Epub ahead of print]

Regulation networks of mitochondrial phosphoproteins were constructed by integrating mitochondrial protein interaction networks and mitochondrial phosphorylation signaling, providing a preliminary survey of how phosphorylation signaling regulates mitochondrial function in beta cells. We present integrated resources including the protein composition and signaling pathways of mitochondria which can be used to understand the role of mitochondria in GSIS.

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04/13/2010

Gu C, Stein GH, Pan N, Goebbels S, Hörnberg H, Nave KA, Herrera P, White P, Kaestner KH, Sussel L, Lee JE.
Cell Metab. 2010 Apr 7;11(4):298-310.

Compared to Mycophenolate Mofetil and Cyclosporin A, Everilimus and Sirolimus demonstrate lower toxicity effect on INS-1 cells and rat pancreatic islets in vitro and Everolimus is expected as a new type of immunosuppressive agent used in clinical islet transplantation.

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