14th Servier-IGIS symposium

ISLET INFLAMMATION

Saint-Jean-Cap-Ferrat, 21-24 March 2013

Thursday, 21 March 2013

OPENING OF SYMPOSIUM
18:15-18:30 Laurence Alliot (Paris) – Erol Cerasi (Jerusalem)

OPENING LECTURE
Chair: Pierre Freychet (Nice)

18:30-19:10 Shizuo Akira (Osaka): Regulation of the innate immune response
19:10-19:30 Discussion

Friday, 22 March 2013

LECTURE
Chair: Piero Marchetti (Pisa)

8:30-9:10 Myung-Shik Lee (Seoul): Role of pancreatic beta-cell death and inflammation in diabetes
9:10-9:30 Discussion

SESSION 1 ENVIRONMENT, INFLAMMATION & METABOLISM
Chair: Eicke Latz (Bonn)

9:30-9:50 Anthony Ferrante (New York): The adipose tissue – macrophage interplay
9:50-10:10 Discussion

10:10-10:30 Christian Herder (Düsseldorf): Pro- and anti-inflammatory cytokines and risk of type 2 diabetes: data from epidemiological cohort studies
10:30-10:50 Discussion

10:50-11:50 Posters 1 & Coffee

11:50-12:10 Myra Nimmo (Loughborough): The role of exercise and physical activity on the IL-6
system and other mediators of inflammation

12:10-12:30 Discussion

12:30-12:50 Rémy Burcelin (Toulouse): Metagenome and metabolism
12:50-13:10 Discussion

SESSION 2 INFLAMMATION OF THE ISLET – I
Chair: Emmanuel van Obberghen (Nice)

15:30-15:50 Christian Boitard (Paris): Diabetes: the islet – immune cross talk
15:50-16:10 Discussion

16:10-16:30 Per-Olof Berggren (Stockholm): Non-invasive longitudinal imaging of the islet immune response
16:30-16:50 Discussion

16:50-17:10 Jerry Nadler (Norfolk): Interaction between cytokines and inflammatory cells in islet dysfunction, insulin resistance and vascular disease
17:10-17:30 Discussion

17:30-17:50 Coffee

17:50-18:10 Decio Eizirik (Brussels): Mechanisms of inflammation-induced beta-cell damage
18:10-18:30 Discussion

18:30-18:50 Raghavendra Mirmira (Indianapolis): Post-transcriptional mechanisms in cytokine-induced islet dysfunction
18:50-19:10 Discussion

Saturday, 23 March 2013

SESSION 3 INFLAMMATION OF THE ISLET – II
Chair: Chantal Mathieu (Leuven)

8:30-8:50 Thomas Mandrup-Poulsen (Copenhagen): Cytokine-induced iron import sensitizes beta-cells to inflammatory attack
8:50-9:10 Discussion

9:10-9:30 Roberto Mallone (Paris): Adaptive immune responses against beta-cells in type 1 diabetes
9:30-9:50 Discussion

9:50-10:10 Barbara Brooks-Worrell (Seattle): Islet autoimmunity in phenotypic type 2 patients
10:10-10:30 Discussion

10:30-11:30 Posters 2 & Coffee

11:30-11:50 Chantal Mathieu (Leuven): Vitamin D and diabetes
11:50-12:10 Discussion

12:10-12:30 Ichiro Manabe (Tokyo): Mechanism of palmitate-induced islet inflammation
12:30-12:50 Discussion

SESSION 4 THERAPEUTIC APPROACHES
Chair: Domenico Accili (New York)

15:30-15:50 Luke O’Neill (Dublin): Innate immune receptors and metabolic regulation
15:50-16:10 Discussion

16:10-16:30 Mark Febbraio (Melbourne): Targeting gp130 to prevent inflammation and promote insulin action
16:30-16:50 Discussion

16:50-17:10 Shin-Ichiro Imai (St. Louis): Mammalian sirtuins and metabolic inflammation
17:10-17:30 Discussion

17:30-17:50 Coffee

CLOSING LECTURE
Chair: Gökhan Hotamisligil (Boston)

17:50-18:10 Mark Donath (Basel): Targeting inflammation in the treatment of diabetes – Outlooks
18:10-18:30 Discussion

CLOSURE OF SYMPOSIUM
18:30 Erol Cerasi (Jerusalem)