Archives for July 2014

Papers of Interest

Today, Bo Ahren (Lund University), is highlighting 2 papers

The secretory deficit in islets from db/db mice is mainly due to a loss of responding beta cells.Do OH, et al. Diabetologia. 2014;57:1400-1409.The nature of the beta-cell defect in type 2 diabetes is still not completely understood. In this new study, the authors present novel findings that the beta-cell defect in the db/db mouse model is associated with reduced calcium response to glucose in association with a reduction in syntaxin-1A. Read the full article »

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.Madiraju …